• Bariatric surgery reduces fasting total fatty acids and increases n-3 polyunsaturated fatty acids in morbidly obese individuals 

      Hovland, Anders; Nestvold, Torunn Kristin; Bohov, Pavol; Trøseid, Marius; Aukrust, Pål; Berge, Rolf Kristian; Nielsen, Erik Waage; Retterstøl, Kjetil; Lappegård, Knut Tore (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-10-25)
      Background: <br> Obesity is a global pandemic leading to increased mortality and increased risk of cardiovascular disease. Bariatric surgery is an established treatment of obesity leading to weight loss and reduction of mortality. To further elucidate how bariatric surgery improves metabolic control, we explored the fatty acid (FA) profiles in morbidly obese subjects treated with lifestyle ...
    • Cost-effectiveness and quality of life in surgeon versus general practitioner-organised colon cancer surveillance: a randomised controlled trial 

      Augestad, Knut Magne; Norum, Jan; Dehof, Stefan; Aspevik, Ranveig; Ringberg, Unni; Nestvold, Torunn Kristin; Vonen, Barthold; Skrøvseth, Stein Olav; Lindsetmo, Rolv-Ole (Journal article; Tidsskriftartikkel; Peer reviewed, 2013-04-04)
      Objective: To assess whether colon cancer follow-up can be organised by general practitioners (GPs) without a decline in the patient's quality of life (QoL) and increase in cost or time to cancer diagnoses, compared to hospital follow-up. Design: Randomised controlled trial. Setting: Northern Norway Health Authority Trust, 4 trusts, 11 hospitals and 88 local communities. Participants: Patients ...
    • Major increase in microbiota-dependent proatherogenic metabolite TMAO one year after bariatric surgery 

      Trøseid, Marius; Hov, Johannes Espolin Roksund; Nestvold, Torunn Kristin; Thoresen, Hanne; Berge, Rolf Kristian; Svardal, Asbjørn M.; Lappegård, Knut Tore (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-04-15)
      Background: Trimethylamine-N-oxide (TMAO) is formed in the liver from trimethylamine (TMA), a product exclusively generated by the gut microbiota from dietary phosphatidylcholine and carnitine. An alternative pathway of TMAO formation from carnitine is via the microbiota-dependent intermediate g-butyrobetaine (gBB). Elevated TMAO levels are associated with cardiovascular disease (CVD), but little ...
    • Plasma Lipopolysaccharide Is Closely Associated With Glycemic Control and Abdominal Obesity: Evidence from bariatric surgery 

      Trøseid, Marius; Nestvold, Torunn Kristin; Rudi, Knut; Thoresen, Hanna; Nielsen, Erik Waage; Lappegård, Knut Tore (Journal article; Tidsskriftartikkel; Peer reviewed, 2013-10-15)
      OBJECTIVE It is of vital importance to elucidate the triggering factors of obesity and type 2 diabetes to improve patient care. Bariatric surgery has been shown to prevent and even cure diabetes, but the mechanism is unknown. Elevated levels of lipopolysaccharide (LPS) predict incident diabetes, but the sources of LPS are not clarified. The objective of the current study was to evaluate the ...
    • A study of changes in glucose metabolism and inflammatory markers in morbidly obese patients undergoing bariatric surgery 

      Nestvold, Torunn Kristin (Doctoral thesis; Doktorgradsavhandling, 2015-06-08)
      Summary Obesity is considered a worldwide pandemic. Morbidly obese patients are at risk of developing comorbidity such as diabetes mellitus type 2, hypertension and cardiovascular disease. The mechanisms behind the development of such complications in morbidly obese patients are still not fully understood, but low-grade inflammation and visceral adiposity are both involved. Effective treatment that ...
    • Translation and validation of the Norwegian version of the postoperative quality of recovery score QoR-15 

      Bergestuen, Linda; Moger, Thomas A. Waksvik; Oterhals, Kjersti; Pfeffer, Frank; Nestvold, Torunn Kristin; Norderval, Stig; Nymo, Linn Såve; Havnes, Kjerstin; Lassen, Kristoffer; Breivik, Kyrre (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-09-08)
      Background As patient-centered care gains more attention, assessing the patient's perspective on their recovery has become increasingly important. In response to the need for a reliable and valid patient reported outcome measurement tool for major surgical resections in Norway. The Norwegian Registry for Gastrointestinal Surgery (NORGAST) initiated a project to translate and evaluate QoR-15's ...